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English: The inhibitory mechanism of serpins involved a large conformation change.The serpin (white) first binds a protease (grey) with the reactive centre loop (blue). When cleaved by the protease, this loop rapidly inserts into the A-sheet (light blue), deforming and inhibiting the protease. (PDB: 1K9O​, 1EZX​)
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Xigasho Shaqadayda
Qoraa Thomas Shafee

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I, the copyright holder of this work, hereby publish it under the following license:
w:en:Creative Commons
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This file is licensed under the Creative Commons Attribution 4.0 International license.
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inception Ingiriisi

13 Diseembar 2015

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image/png

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Taariikhda/WaqtigaSawir yarCabirkaIsticmaaleKa hadalka
kan hadda23:04, 19 Maaj 2016Sawirka yar nuuciisa ahaa 23:04, 19 Maaj 20163,000 × 3,000 (2.83 MB)Evolution and evolvabilityColour tweaks
09:55, 22 Diseembar 2015Sawirka yar nuuciisa ahaa 09:55, 22 Diseembar 20151,800 × 1,868 (1.13 MB)Evolution and evolvabilityHigher resolution and darker grey for protease
00:36, 20 Diseembar 2015Sawirka yar nuuciisa ahaa 00:36, 20 Diseembar 20151,083 × 1,125 (498 KB)Evolution and evolvabilityblue arrow (inkeeping with Serpin mechanism.png scheme)
11:52, 13 Diseembar 2015Sawirka yar nuuciisa ahaa 11:52, 13 Diseembar 20151,083 × 1,125 (496 KB)Evolution and evolvabilityA-sheet colour
11:33, 13 Diseembar 2015Sawirka yar nuuciisa ahaa 11:33, 13 Diseembar 20151,150 × 1,111 (462 KB)Evolution and evolvabilityCross-wiki upload from en.wikipedia.org

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